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Cayman Chemical MebhydrolIn1 5-naphthalen 1g
Supplier: Cayman Chemical 402811 G
A histamine H1 receptor antagonist (Ki = 7.6 nM); selective for the histamine H1 receptor over muscarinic acetylcholine receptors (mAChRs; Ki = 180 nM); inhibits acid sphingomyelinase in H4 neuroglioma cells at 10 µM; binds to the FXR ligand-binding domain (Kd = 9.87 µM); inhibits GW 4064-induced transactivation of FXR in HEK293T cells expressing the human receptor; binds to Zika virus RdRp (Kd = 22.62 µM) and reduces viral replication in Zika-infected Vero cells (EC50 = 5.14 µM); decreases blood glucose and plasma HbA1c levels in db/db diabetic mice at 30 mg/kg
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