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Abcam Mecamylamine hydrochloride, non-competitive antagonist of nicotinic receptors, 10MG

Supplier:  Abcam AB12045910MG

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MW 203.75 Da. Non-competitive, non-selective antagonist of nicotinic actelycholine receptors (nAChRs). Blood-brain barrier permeable. Blocks various different nAChR types, (IC₅₀ values are 640 nM, 2.5 μM, 3.6 μM and 6.9 μM at α3β4, α4β2, α3β2 and α7 receptors, respectively). Blocks most physiological, behavioural and reinforcing effects of nicotine. Displays antidepressant-like effects in mice.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-270-7577


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