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Medchemexpress LLC MedChemExpress Daraxonrasib, RAS (ON) Inhibitor, Orally Active, Non-Covalent
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Catalog No. NC3991737
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Daraxonrasib (RMC-6236) is an orally active, non-covalent RAS (ON) inhibitor. It disrupts the interaction of wild-type or mutant RAS proteins with the RAS binding domain of BRAF, inhibits pERK, and exhibits anti-tumor activity against KRAS mutant tumors.

  • Orally active, non-covalent RAS (ON) inhibitor.
  • Disrupts interaction of wild-type or mutant RAS proteins with BRAF’s RAS binding domain.
  • Inhibits pERK.
  • Has anti-tumor activity against KRAS mutant tumors.
  • Potently inhibits the growth of KRAS mutant cancer cell lines HPAC and Capan-2.
  • Shows dose-dependent antitumor activity in various human tumor xenograft models harboring prevalent KRAS mutations.

Catalog No. NC3991737 Supplier Medchemexpress LLC Supplier No. HY1484392X400MG
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Daraxonrasib (RMC-6236) is an orally active, non-covalent RAS (ON) inhibitor. It disrupts the interaction of wild-type or mutant RAS proteins with the RAS binding domain of BRAF, inhibits pERK, and exhibits anti-tumor activity against KRAS mutant tumors.

  • Orally active, non-covalent RAS (ON) inhibitor.
  • Disrupts interaction of wild-type or mutant RAS proteins with BRAF’s RAS binding domain.
  • Inhibits pERK.
  • Has anti-tumor activity against KRAS mutant tumors.
  • Potently inhibits the growth of KRAS mutant cancer cell lines HPAC and Capan-2.
  • Shows dose-dependent antitumor activity in various human tumor xenograft models harboring prevalent KRAS mutations.

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