Medchemexpress LLC Medroxyprogesterone acetate | 71-58-9 | 99.9% | 5 G

Supplier:  Medchemexpress LLC HYB04695G

Medroxyprogesterone acetate is a synthetic steroid that interacts with progesterone, androgen, and glucocorticoid receptors. It is used in research and has shown activity in various cell lines, demonstrating both agonistic and antiproliferative effects. Studies have explored its impact on endothelial cells, where it can inhibit eNOS expression, leukocyte adhesion, and NF-κB nuclear translocation.

• Acts as a synthetic steroid.
• Interacts with progesterone, androgen, and glucocorticoid receptors.
• Exhibits antiproliferative activity against certain human cancer cells.
• Can inhibit eNOS expression in steroid-deprived human endothelial cells.
• Reduces leukocyte adhesion to human endothelial cells.
• Decreases NF-κB nuclear translocation in human endothelial cells.

Catalog No. 50-004-05404