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Medchemexpress LLC Mefloquine (hydrochloride) | 51773-92-3 | 99.98% | 414.77 | 500 MG
Supplier: Medchemexpress LLC HY17437A500MG
Mefloquine hydrochloride is a quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. It acts as a K+ channel antagonist and is suitable for research in malaria, systemic lupus erythematosus, and cancer. It selectively inhibits prostate cancer cell growth and shows higher anti-SARS-CoV-2 activity than Hydroxychloroquine. Animal studies indicate it can reverse lower vertebral cancellous bone volume.
- Quinoline antimalarial agent
- Anti-SARS-CoV-2 entry inhibitor
- K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM
- Selectively inhibits prostate cancer cell growth with an IC50 of ~10 μM
- Induces hyperpolarization of mitochondrial membrane potential (MMP) and ROS generation
- Shows higher anti-SARS-CoV-2 activity than Hydroxychloroquine
- Can be used for malaria, systemic lupus erythematosus and cancer research
- Reverses lower vertebral cancellous bone volume and bone formation in old mice
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