Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 50464019

AdipoGen CD40L (human) (multimeric) (rec.)
SDP

Supplier:  AdipoGen AG40B0010C010

Encompass_Preferred

CD40L (human) (multimeric) (rec.), AdipoGen Life Sciences. Protein. Human CD40L (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG-tag. Source: CHO cells. Endotoxin content: <0.01EU/g purified protein (LAL test; Lonza). Lyophilized. Contains PBS Binds to human CD40. Purity: >95% (SDS-PAGE). MultimericCD40L is a high activity construct in which two trimeric CD40 ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively simulates the natural membrane-assisted aggregation of CD40L in vivo. It provides a simple and equally potent alternative to combinations. MultimericCD40L has shown to suppress alum-induced IL-1beta release and caspase-1 activation in a dose-, CD40- and time dependent manner, without affecting BMDM viability. It also effectively suppressed the inflammasome function triggered by NLRP3 activators.

Catalog No. 50-464-019


May include imposed supplier surcharges.
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.