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Apexbio Technology LLC Megestrol Acetate 595-33-5 1g
Supplier: Apexbio Technology LLC B13771000
Megestrol Acetate (CAS 595-33-5) is a synthetic progestin utilized to downregulate nuclear and cytoplasmic androgen receptor activity It modulates hormone receptor-mediated processes thereby impacting cellular metabolic and signaling pathways Megestrol Acetate exerts its biological activity primarily by inducing apoptosis and disrupting cell cycle progression In in vitro studies using HepG2 cell lines Megestrol Acetate demonstrates proliferation inhibition with an IC50 value of approximately 260 M Based on these pharmacological properties Megestrol Acetate holds research potential in studies of cancer cachexia hepatocellular carcinoma and the investigation of tumor growth mechanisms
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