Medchemexpress LLC Melagatran | 159776-70-2 | 99.3% | 429.51 g·mol⁻¹ | C22H31N5O4 | 5 MG

Supplier:  Medchemexpress LLC HY1290565MG

Melagatran is a reversible, selective, orally active small-molecule direct inhibitor of thrombin for preclinical research. It binds the thrombin active site (Ki ≈ 2 nM), blocking thrombin-mediated conversion of fibrinogen to fibrin and modulating NF-κB and AP-1 pathways. Typical research applications include thrombosis, atherosclerosis, and ischemic brain injury models.

• Direct and potent thrombin inhibition with low nanomolar Ki.
• Suitable for in vitro and in vivo cardiovascular research.
• High reported purity (~99.3%) for reliable results.
• Solid powder form facilitating storage and handling.
• Storage recommendations: powder at -20°C; solutions at -80°C for long-term storage.

Catalog No. 50-002-62449