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Melphalan, Tocris Bioscience™

Catalog No. 461950
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50 mg
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Catalog No. Quantity
46-195-0 50 mg
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Catalog No. 46-195-0 Supplier R&D Systems Supplier No. 4619/50
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Description

DNA alkylating agent; cytotoxic and antineoplastic

DNA alkylating agent; induces cytotoxicity through the formation of stable interstrand and intrastrand crosslinks within DNA. Inhibits growth of PC-3 cells (IC50 values are 0.074 and 0.77 μg/ml for sequential dosing and single dosing respectively).

Chemical Identifiers

CAS 148-82-3
Molecular Formula C13H18Cl2N2O2
Molecular Weight (g/mol) 305.199
InChI Key SGDBTWWWUNNDEQ-LBPRGKRZSA-N
Synonym melphalan, alkeran, melfalan, phenylalanine mustard, l-sarcolysine, l-pam, l-sarcolysin, l-phenylalanine mustard, levofalan, p-l-sarcolysin
PubChem CID 460612
ChEBI CHEBI:28876
IUPAC Name (2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid
SMILES C1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl

Specifications

Quantity 50 mg
Formula Weight 305.2
Percent Purity >95%
Chemical Name or Material Melphalan

Safety and Handling

Recommended Storage Store at Room Temperature
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