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Sigma Aldrich Fine Chemicals Biosciences Membrane Scaffold Protein5MG

Supplier:  Sigma Aldrich Fine Chemicals Biosciences MSP085MG

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Nanodiscs are non-covalent structures that contain a phospholipid bilayer and a membrane scaffold protein (MSP) a genetically engineered protein which mimics the function of Apolipoprotein A-1 (ApoA-1). The first MSP MSP1 was engineered with its sequence based on the sequence of A-1 but without the globular N-terminal domain of native A-1. The MSP1E3D1 variant of MSP1 differs from MSP1 in the following facetsIt deletes the first 11 amino acids in the Helix 1 portion (referred to as H0.5 in the accompanying figure) of the original MSP1 sequence3 (which is known separately as MSP1D1).It repeats the Helix 4 (H4) Helix 5 (H5) and Helix 6 (H6) sequences of the original MSP1 sequence between the parent Helix 6 (H6) and Helix 7 (H7) segments of MSP1D1.

Catalog No. 50-290-4394


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