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Medchemexpress LLC Men 10376 TFA | 99.7% | 1195.25 | 5 MG
Supplier: Medchemexpress LLC HYP1276A5MG
Men 10376 TFA is a selective tachykinin NK-2 receptor antagonist. It exhibits a Ki of 4.4 μM for the rat small intestine NK-2 receptor, with low selectivity for NK-1 and NK-3 receptors. This compound antagonizes increases in bladder motility produced by NK-2 receptor agonists in rats.
- Selective tachykinin NK-2 receptor antagonist
- Ki of 4.4 μM for rat small intestine NK-2 receptor
- Low selectivity for NK-1 and NK-3 receptors (Ki >10 μM)
- Antagonizes bladder motility increase in vivo
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