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Medchemexpress LLC (-)-Menthol | 2216-51-5 | 99.79% | C10H20O | 1 ML

Supplier: Medchemexpress LLC HY7516110MM/1ML
(-)-Menthol is a key component of peppermint oil. It binds and activates transient receptor potential melastatin 8 (TRPM8), a Ca2+-permeable nonselective cation channel, leading to an increase in intracellular Ca2+ levels. It also exhibits antitumor activity and can enhance 1α,25(OH)2D3-mediated growth inhibition in LNCaP cells.
- Activates TRPM8, a Ca2+-permeable nonselective cation channel
- Increases intracellular Ca2+ levels
- Exhibits antitumor activity
- Enhances 1α,25(OH)2D3-mediated growth inhibition
- Modulates bcl-2 and p21 expression
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