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Medchemexpress LLC Mepyramine maleate (pyrilamine maleate) | 59-33-6 | 99.9% | 1 ML
Supplier: Medchemexpress LLC HYB128110MM/1ML
Mepyramine maleate is a first-generation antihistamine that acts as an antagonist of the histamine H1 receptor. It is characterized by specific binding affinities for H1, H2, and H3 receptors.
- Antagonist of the histamine H1 receptor
- Binds to H1 receptor with Kd of 0.8 nM
- Exhibits Kds of 5200 nM for H2 and >3000 nM for H3 receptors
- Decreases InsP levels in CHO-gpH1 cells
- Reduces maximal response to ATP in CHO-gpH1 cells
- Demonstrates analgesic effects in vivo at specific dosages
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