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Mepyramine maleate, Tocris Bioscience™
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Catalog No. 0660100
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Quantity:
100 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective H1 inverse agonist

Selective inverse agonist for the H1 receptor. Inhibits histamine induced inositol phosphate (InsP) production (log EC50 = -7.94) and intracellular calcium mobilization. Sequesters Gq/11 protein, reducing its availability for other receptors associated with the same signaling pathway.

Chemical Identifiers

CAS 59-33-6
Molecular Formula C21H27N3O5
Molecular Weight (g/mol) 401.46
MDL Number MFCD00069333
InChI Key JXYWFNAQESKDNC-BTJKTKAUSA-N
Synonym pyrilamine maleate, mepyramine maleate, anisopyradamine, histosol, minihist, diaminide maleate, paraminyl maleate, antihist, histatex, histine
PubChem CID 5284451
IUPAC Name (2Z)-but-2-enedioic acid; N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine
SMILES OC(=O)\C=C/C(O)=O.COC1=CC=C(CN(CCN(C)C)C2=CC=CC=N2)C=C1

Specifications

Quantity 100 mg
Formula Weight 401.46
Percent Purity >98%
Chemical Name or Material Mepyramine maleate

Safety and Handling

Recommended Storage Store at Room Temperature
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