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Mepyramine maleate, Tocris Bioscience™

Catalog No. 0660100
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100 mg
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Catalog No. Quantity
06-601-00 100 mg
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Catalog No. 06-601-00 Supplier R&D Systems Supplier No. 0660/100
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Description

Selective H1 inverse agonist

Selective inverse agonist for the H1 receptor. Inhibits histamine induced inositol phosphate (InsP) production (log EC50 = -7.94) and intracellular calcium mobilization. Sequesters Gq/11 protein, reducing its availability for other receptors associated with the same signaling pathway.

Chemical Identifiers

CAS 59-33-6
Molecular Formula C21H27N3O5
Molecular Weight (g/mol) 401.46
MDL Number MFCD00069333
InChI Key JXYWFNAQESKDNC-BTJKTKAUSA-N
Synonym pyrilamine maleate, mepyramine maleate, anisopyradamine, histosol, minihist, diaminide maleate, paraminyl maleate, antihist, histatex, histine
PubChem CID 5284451
IUPAC Name (2Z)-but-2-enedioic acid; N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine
SMILES OC(=O)\C=C/C(O)=O.COC1=CC=C(CN(CCN(C)C)C2=CC=CC=N2)C=C1

Specifications

Quantity 100 mg
Formula Weight 401.46
Percent Purity >98%
Chemical Name or Material Mepyramine maleate

Safety and Handling

Recommended Storage Store at Room Temperature
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