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Apexbio Technology LLC Meropenem trihydrate 119478-56-7 10mM (in 1mL H2O)
Supplier: Apexbio Technology LLC B12175.1
Meropenem trihydrate is a broad-spectrum carbapenem antibiotic that kills bacteria by inhibiting cell wall synthesis It targets penicillin-binding proteins (PBPs) disrupting peptidoglycan cross-linkage leading to bacterial death Effective against Gram-negative bacteria like Escherichia coli Klebsiella pneumoniae and Enterobacter aerogenes with MIC90 values between 0 03 M and 0 25 M it also inhibits Gram-positive strains like Streptococcus pneumoniae (MIC90 0 015 M) and anaerobic species MIC values are pH-dependent averaging 0 06 M at pH 5 5 and 0 03 M at pH 7 5 Meropenem trihydrate is used in antimicrobial susceptibility testing microbiological studies and research on carbapenem resistance and -lactamase stability
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