Thermo Scientific Chemicals MES, 0.2M buffer soln., pH 6.0

Description

CAS: 145224-94-8 | C6H15NO5S | 213.248 g/mol

MES is used as a running buffer for resolving very small proteins (ex: 13 kDa) on bis-tris gels. Also used in cation-exchange chromatography and as a biological buffer in plant cell cultures. Used in various protein characterization assays. MES is also useful as a non-coordinating buffer in chemistry involving metal ions, as many common buffers (e.g. phosphate and acetate) readily form coordination complexes. MES only weakly binds Ca, Mg, Mn, and it has negligible binding with Cu(II).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
MES is used as a running buffer for resolving very small proteins (ex: 13 kDa) on bis-tris gels. Also used in cation-exchange chromatography and as a biological buffer in plant cell cultures. Used in various protein characterization assays. MES is also useful as a non-coordinating buffer in chemistry involving metal ions, as many common buffers (e.g. phosphate and acetate) readily form coordination complexes. MES only weakly binds Ca, Mg, Mn, and it has negligible binding with Cu(II).

Solubility
Soluble in water (∼1.3 M).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 145224-94-8
• Molecular Formula: C6H15NO5S
• Molecular Weight (g/mol): 213.248
• MDL Number: MFCD00283848
• InChI Key: MIIIXQJBDGSIKL-UHFFFAOYSA-N
• PubChem CID: 16218417
• IUPAC Name: 2-morpholin-4-ylethanesulfonic acid;hydrate
• SMILES: C1COCCN1CCS(=O)(=O)O.O

• Color: Colorless
• Concentration: 0.2 M
• pH: 6.0
• Physical Form: Liquid
• Quantity: 500 mL
• Solubility Information: Soluble in water (∽1.3 M).
• Chemical Name or Material: MES buffer soln.

Safety and Handling

Hazard Category	Warning
Hazard Statement	GHS H Statement H315-H319 Causes skin irritation. Causes serious eye irritation.
Precautionary Statement	GHS P Statement P280-P305+P351+P338-P362-P321-P332+P313-P337+P313 Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Take off contaminated clothing and wash before reuse. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Get medical advice/attention.
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only