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Cayman Chemical MesorIdazIn 50mg
SDP

Supplier:  Cayman Chemical 3137050 MG

Encompass_Preferred

A multi-kinase inhibitor (IC50s 0 3 16 1 5 8 7 and 1 4 nM for EGFR ErbB2 KDR FLT4 and EphB4 respectively) selective for these kinases over a panel of 10 tyrosine kinases and 55 serine/threonine kinases at 10 M inhibits growth of A431 cells expressing wild-type EGFR and H1975 NSCLC cells expressing both EGFRL858R and EGFRT790M (IC50s 13 and 920 nM respectively) inhibits tumor growth and EGFR phosphorylation in an H1975 mouse xenograft model at 10 30 and 100 mg/kg

Catalog No. 50-299-0752


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