Apexbio Technology LLC Mesoridazine(Synonyms: Serentil, Mesoridazine besylate, TPS-23), 10mM (in 1mL DMSO), CAS: 5588-33-0.

Supplier:  Apexbio Technology LLC A87025.1

Mesoridazine (CAS 5588-33-0) is a dopaminergic antagonist primarily targeting dopamine D2 receptors (K d 19 nM) As an active metabolite of the atypical antipsychotic thioridazine mesoridazine demonstrates marked inhibitory effects on both pre- and postsynaptic dopamine receptors impacting dopamine and acetylcholine neurotransmission Furthermore mesoridazine engages histamine H1 (K d 1 8 nM) muscarinic acetylcholine (K d 69 nM) 1-adrenergic (K d 2 nM) and 2-adrenergic (K d 1600 nM) receptors Its receptor profile makes mesoridazine valuable for neuroscience research into antipsychotic mechanisms and neurotransmitter regulation

Catalog No. 50-000-60586