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Cayman Chemical MetaprIston 10mg
Supplier: Cayman Chemical 3638010 MG
An active metabolite of mifepristone; an antagonist of human glucocorticoid and progesterone receptors with relative affinities of 61 and 21%, respectively, compared to mifepristone; decreases the proliferation of A375 and B16/F10 cells (IC50s = 57.4 and 75.8 µM, respectively); induces cell-cycle arrest at the G1 phase in B16/F10 cells at 80 µM; decreases the number of lung metastases in a B16/F10 murine model of lung metastasis at 2.5, 10, and 50 mg/kg per day
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