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Medchemexpress LLC Metaproterenol (hemisulfate) | 5874-97-5 | 99.4% | 100 MG
SDP

Supplier:  Medchemexpress LLC HYB1276100MG

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Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. It also exhibits anti-inflammatory activity.

  • Functions as a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM.
  • Possesses anti-inflammatory activity.
  • Enhances β-arrestin2 and its interaction with IκBα in high glucose-induced THP-1 cells and bone marrow macrophages.
  • Downregulates NF-κB in high glucose-induced THP-1 cells and bone marrow macrophages.
  • Attenuates monocyte activation and pro-inflammatory and pro-fibrotic responses in the kidneys and heart of Zucker diabetic fatty rats, potentially offering protective effects against diabetic renal and cardiovascular complications.

Catalog No. 50-004-11873


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