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Apexbio Technology LLC Metformin HCl 1115-70-4 10g
Supplier: Apexbio Technology LLC B197010000
Metformin hydrochloride (Metformin HCl CAS 1115-70-4) is a widely studied small molecule employed in biomedical research primarily for investigating glucose metabolism and type 2 diabetes mechanisms It acts through selective inhibition of hepatic gluconeogenesis without directly increasing insulin secretion The molecular targets include activation of AMP-activated protein kinase (AMPK) subsequently suppressing acetyl-CoA carboxylase (ACC) activity attenuating lipid biosynthesis and promoting fatty acid oxidation Additionally metformin inhibits mitochondrial glycerophosphate dehydrogenase (mGPD) changing cellular redox status and reducing lactate-driven gluconeogenesis pathways Key research applications of Metformin HCl include studies on glucose homeostasis metabolic disorders and AMPK signaling cascades
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