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Medchemexpress LLC Metformin (hydrochloride) | 1115-70-4 | 100.0% | 165.62 | 100 MG
Supplier: Medchemexpress LLC HY17471A100MG
Metformin hydrochloride is a compound that inhibits the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhanced insulin sensitivity, useful in type 2 diabetes research. It also lowers glucose by inhibiting Ras-related protein 1 (Rap1) in SF1 hypothalamic neurons and reduces liver oxidative stress, inflammation, and apoptosis. Additionally, it regulates autophagy and inhibits renal cell carcinoma growth by activating AMPK and inhibiting the mTOR pathway.
- Inhibits mitochondrial respiratory chain
- Activates AMPK and enhances insulin sensitivity
- Used for type 2 diabetes research
- Lowers glucose by inhibiting Rap1
- Reduces liver oxidative stress, inflammation, and apoptosis
- Regulates autophagy by activating AMPK
- Inhibits mTOR signaling pathway
- Induces tumor cell autophagy
- Inhibits renal cell carcinoma growth in vitro and in vivo
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