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Cayman Chemical Metformin (hydrochloride), 1115-70-4, 5 g
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Supplier:  Cayman Chemical 131185

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Molecular Formula C4H11N5 • HCl, Purity ≥98%, Formula Weight 165.6, Synonyms: 1,1-Dimethylbiguanide hydrochloride; A biguanide with diverse biological activities; increases hepatic AMPK activity and reduces blood glucose by more than 50% in a liver kinase B1-dependent manner in mice fed normal and high-fat diets, respectively, and reduces blood glucose by 40% in ob/ob mice at 250 mg/kg; reduces weight gain, hepatic lipid droplet content, and total cholesterol, LDL cholesterol, and triglyceride levels in the plasma of diet-induced obese mice at 10 or 50 mg/kg per day; reverses increased hepatic triglyceride and apolipoprotein A5 levels, as well as hepatic steatosis, in an ob/ob mouse model of NAFLD; reduces tumor growth in an HCT116 p53-- mouse xenograft model at 250 mg/kg.

Catalog No. NC0552835


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