Methanesulfonyl chloride, 98%

Catalog No.	Quantity
AAA1338336	500 g
AAA1338322	100 g

Catalog No. AAA1338336 Supplier Thermo Scientific Chemicals Supplier No. A1338336

Description

CAS: 124-63-0 | CH3ClO2S | 114.54 g/mol

Methanesulfonyl chloride is used as a reagent for conversion of alcohols to mesylate esters such as methanesulfonate, which is an intermediate in substitution reactions, elimination reactions, reductions, and rearrangement reactions viz. Beckmann rearrangement. It is an electrophile and acts as a source of CH₃SO₂⁺ group. It is also used to prepare beta-chloro sulfones, methanesulfonamide and heterocyclic compounds containing five membered sultones.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Methanesulfonyl chloride is used as a reagent for conversion of alcohols to mesylate esters such as methanesulfonate, which is an intermediate in substitution reactions, elimination reactions, reductions, and rearrangement reactions viz. Beckmann rearrangement. It is an electrophile and acts as a source of CH₃SO₂⁺ group. It is also used to prepare beta-chloro sulfones, methanesulfonamide and heterocyclic compounds containing five membered sultones.

Solubility
Miscible with alcohol, ether and organic solvents. Immiscible with water.

Notes
Moisture sensitive. Store in a cool place. Incompatible with strong bases, oxidizing agents and alcohols. It is a lachrymator and reacts with water.

Specifications

Chemical Identifiers

• CAS: 124-63-0
• Molecular Formula: CH3ClO2S
• Molecular Weight (g/mol): 114.54
• MDL Number: MFCD00007454
• InChI Key: QARBMVPHQWIHKH-UHFFFAOYSA-N
• Synonym: mesyl chloride, methylsulfonyl chloride, methyl sulfochloride, methanesulphonyl chloride, chloro methyl sulfone, methanesulfuryl chloride, methanesulfonic acid chloride, methyl sulfonyl chloride, chloromethyl sulfone, mesylchloride
• PubChem CID: 31297
• IUPAC Name: methanesulfonyl chloride
• SMILES: CS(Cl)(=O)=O

• Melting Point: -33°C
• Density: 1.477
• Boiling Point: 161°C
• Flash Point: 97°C (206°F)
• Odor: Pungent
• Assay Percent Range: 98%
• Refractive Index: 1.452
• Quantity: 500 g
• UN Number: UN3246
• Beilstein: 506297
• Sensitivity: Moisture sensitive
• Merck Index: 14,5955
• Solubility Information: Miscible with alcohol,ether and organic solvents. Immiscible with water.
• Formula Weight: 114.55
• Percent Purity: 98%
• Physical Form: Liquid
• Chemical Name or Material: Methanesulfonyl chloride

Safety and Handling

Hazard Category	H290-H301+H311-H314-H317-H330-H335
Hazard Statement	GHS H Statement H300-H310-H330-H314-H318 Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P234-P260-P264b-P270-P271-P272-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P390-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: METHANESULFONYL CHLORIDE
EINECSNumber	204-706-1
RTECSNumber	PB2790000
TSCA	Yes
storageNote1	Moisture Sensitive
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only