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Medchemexpress LLC Methanone (2-chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoro-2-pyrimidinyl)-1,4,6,7-tetrahydro-4-methyl-triazolo[4,5-c]pyridin-5-yl) | 1627902-21-9 | MFCD31556312 | 99.3% | 440.8 g/mol | C18H13ClF4N6O | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1175085MG

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JNJ-54175446 is a brain-penetrant, selective P2X7 receptor antagonist used as a research tool to study neuroinflammation and central nervous system disorders. It has been characterized in preclinical and clinical research for its pharmacodynamic effects in the brain.

  • Potent P2X7 antagonist with reported pIC50 8.46 (human) and 8.81 (rat).
  • Brain penetrant, suitable for CNS pharmacology studies.
  • High reported purity for research assays (99.3%).
  • Solid, light yellow to yellow appearance for solid handling and storage.
  • Molecular weight 440.8 g/mol and formula C18H13ClF4N6O.
  • For research use only; not intended for clinical or therapeutic use.

Catalog No. 50-002-27087


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