Methicillin sodium salt, 90+%

Catalog No.	Quantity
AAJ6641403	1 g

Catalog No. AAJ6641403 Supplier Thermo Scientific Chemicals Supplier No. J6641403

Description

CAS: 132-92-3 | C17H19N2NaO6S | 402.40 g/mol

Targets primarily the cell wall of Gram-positive organisms especially Staphylococcus aureus. Methicillin is used to study bacterium susceptibility, and to inhibit cell-wall synthesis. PBP's are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Methicillin Sodium Salt is inactivated by gastric acid so it is given to cells by other means in which gastric acid is not present in vitro.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Targets primarily the cell wall of Gram-positive organisms especially Staphylococcus aureus. Methicillin is used to study bacterium susceptibility, and to inhibit cell-wall synthesis. PBP′s are enzymes which catalyze a pentagl

Specifications

Chemical Identifiers

• CAS: 132-92-3
• Molecular Formula: C17H19N2NaO6S
• Molecular Weight (g/mol): 402.40
• MDL Number: MFCD07787409
• InChI Key: MGFZNWDWOKASQZ-UMLIZJHQSA-M
• Synonym: Sodium (2,6-dimethoxyphenyl)penicillin; Sodium methicillin
• PubChem CID: 23667627
• ChEBI: CHEBI:52065
• IUPAC Name: sodium (2S,5R,6R)-6-(2,6-dimethoxybenzamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• SMILES: [Na+].COC1=CC=CC(OC)=C1C(=O)N[C@H]1[C@H]2SC(C)(C)[C@@H](N2C1=O)C([O-])=O

• Type: Methicillin Sodium Salt
• Physical Form: Powder
• Melting Point: 196°C to 197°C (decomposition)
• Color: White
• Quantity: 1 g
• Flash Point: >110°C (230°F)
• Sensitivity: Light sensitive
• Boiling Point: 640°C
• Merck Index: 14,5969
• Solubility Information: Slightly soluble in acetone; Soluble in ethanol or water
• Formula Weight: 402.4
• Percent Purity: 98%
• Chemical Name or Material: Methicillin sodium salt

Safety and Handling

Hazard Category	H315-H317-H319-H334-H335
Hazard Statement	GHS H Statement H334-H335-H315-H319-H317 May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction.
Precautionary Statement	P261-P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P333+P313-P342+P311-P362-P501c
EINECSNumber	205-083-9
RTECSNumber	XH8950000
TSCA	No
storageNote1	-30° to -10°C
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only