Methyl 4-bromocrotonate, tech. 85%

Description

CAS: 1117-71-1 | C5H7BrO2 | 179.01 g/mol

It is a useful synthetic intermediate. It was used in the synthesis of irreversible inhibitors of EGFR and HER-2 tyrosine kinases with enhanced antitumor activities.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a useful synthetic intermediate. It was used in the synthesis of irreversible inhibitors of EGFR and HER-2 tyrosine kinases with enhanced antitumor activities.

Solubility
Slightly soluble in water.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 1117-71-1
• Molecular Formula: C5H7BrO2
• Molecular Weight (g/mol): 179.01
• MDL Number: MFCD00000246,MFCD09998308
• InChI Key: RWIKCBHOVNDESJ-NSCUHMNNSA-N
• Synonym: methyl 4-bromocrotonate, e-methyl 4-bromobut-2-enoate, 4-bromocrotonic acid methyl ester, methyl gamma-bromocrotonate, methyl bromocrotonate, methyl 4-bromo-2-butenoate, 2-butenoic acid, 4-bromo-, methyl ester, methyl 4-bromobut-2-enoate, methyl 2e-4-bromobut-2-enoate, crotonic acid, 4-bromo-, methyl ester
• PubChem CID: 5369175
• IUPAC Name: methyl (E)-4-bromobut-2-enoate
• SMILES: COC(=O)\C=C\CBr

• Density: 1.524
• Boiling Point: 83°C to 85°C (13 mmHg)
• Flash Point: 91°C (195°F)
• Refractive Index: 1.501
• Linear Formula: BrCH₂CH=CHCO₂CH₃
• Quantity: 250 g
• UN Number: UN1760
• Beilstein: 1745755
• Solubility Information: Slightly soluble in water.
• Formula Weight: 179.01
• Percent Purity: 85%
• Grade: Technical
• Chemical Name or Material: Methyl 4-bromocrotonate

Safety and Handling

Hazard Category	H227-H314-H335
Hazard Statement	GHS H Statement H314-H318-H227 Causes severe skin burns and eye damage. Causes serious eye damage. Combustible liquid.
Precautionary Statement	P210-P235-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: III; Proper Shipping Name: CORROSIVE LIQUIDS, N.O.S.
EINECSNumber	214-251-0
RTECSNumber	GQ3120000
TSCA	Yes
Recommended Storage	Keep cold

SDS

RUO – Research Use Only