Methyl acetoacetate, 99%

Catalog No.	Quantity
AAA1369630	250 g
AAA136960B	1000 g
AAA136960I	5000 g

Catalog No. AAA1369630 Supplier Thermo Scientific Chemicals Supplier No. A1369630

Description

CAS: 105-45-3 | C5H8O3 | 116.12 g/mol

Methyl acetoacetate is used as a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.Methyl acetoacetate (MAA) is used for the synthesis of alpha-substituted aceto- acetic esters and cyclic compounds, e.g. pyrazole, pyrimidine and coumarin derivatives.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Methyl acetoacetate is used as a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.Methyl acetoacetate (MAA) is used for the synthesis of alpha-substituted aceto- acetic esters and cyclic compounds, e.g. pyrazole, pyrimidine and coumarin derivatives.

Solubility
Soluble in water

Notes
Store at 2-8°C. Incompatible with oxidizing agents and bases. Protect from light.

Specifications

Chemical Identifiers

• CAS: 105-45-3
• Molecular Formula: C5H8O3
• Molecular Weight (g/mol): 116.12
• MDL Number: MFCD00008784
• InChI Key: WRQNANDWMGAFTP-UHFFFAOYSA-N
• Synonym: methyl acetoacetate, acetoacetic acid methyl ester, methylacetoacetate, methyl 3-oxobutyrate, butanoic acid, 3-oxo-, methyl ester, methyl acetylacetate, methyl acetylacetonate, 3-oxobutanoic acid methyl ester, acetoacetic methyl ester, acetoacetic acid, methyl ester
• PubChem CID: 7757
• IUPAC Name: methyl 3-oxobutanoate
• SMILES: COC(=O)CC(C)=O

• Melting Point: -80°C
• Density: 1.076
• Boiling Point: 170°C
• Flash Point: 70°C (158°F)
• Odor: Pleasant
• Refractive Index: 1.4185
• Linear Formula: CH₃COCH₂CO₂CH₃
• Quantity: 250 g
• Beilstein: 506727
• Merck Index: 14,6009
• Solubility Information: Soluble in water
• Formula Weight: 116.12
• Percent Purity: 99%
• Chemical Name or Material: Methyl acetoacetate

Safety and Handling

Hazard Category	H227-H319
Hazard Statement	GHS H Statement H319-H227 Causes serious eye irritation. Combustible liquid.
Precautionary Statement	P210-P264b-P280-P305+P351+P338-P370+P378q-P501c
EINECSNumber	203-299-8
RTECSNumber	AK5775000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only