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Medchemexpress LLC Methyl-β-cyclodextrin | 128446-36-6 | 100.0% | 1310 (Average) | 50 G
Supplier: Medchemexpress LLC 50GHY101461
Methyl-β-cyclodextrin is a cyclic heptasaccharide that delivers hydrophobic agents by solubilizing non-polar substances. It is extensively used as a cholesterol-depleting reagent, strongly reduces clathrin-dependent endocytosis, and blocks cell migrasome formation. This highly water-soluble compound is effective for cholesterol depletion from cells and increases cell permeability, thereby enhancing the uptake of small molecules like glucose and nanoparticles. In the pharmaceutical industry, it serves as a complexing agent to increase aqueous solubility, bioavailability, and stability of poorly soluble drugs.
- Increases cell permeability for uptake of small molecules and nanoparticles.
- Improves solubility, bioavailability, and stability of poorly soluble drugs.
- Induces caspase-dependent apoptosis in PEL cells.
- Inhibits PEL cell growth and invasion in xenograft mouse models.
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