Methyl indole-3-carboxylate, 99%

Description

CAS: 942-24-5 | C10H9NO2 | 175.187 g/mol

Reactant used for preparation of nitric oxide synthesis (nNOS) inhibitors, protein kinase c alpha (PKCα) inhibitors, inhibitors of the C-terminal domain of RNA polymerase II as antitumor agents, kinase insert domain receptor (KDR) inhibitors, organocatalysts for the anti-Mannich reaction, very late antigen-4 (VLA-4) antagonists, inhibitors of Human 5-Lipoxygenase, serotonin 5-HT4 receptor antagonists and hyaluronidase inhibitors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Reactant used for preparation of nitric oxide synthesis (nNOS) inhibitors, protein kinase c alpha (PKCα) inhibitors, inhibitors of the C-terminal domain of RNA polymerase II as antitumor agents, kinase insert domain receptor (KDR) inhibitors, organocatalysts for the anti-Mannich reaction, very late antigen-4 (VLA-4) antagonists, inhibitors of Human 5-Lipoxygenase, serotonin 5-HT4 receptor antagonists and hyaluronidase inhibitors.

Solubility
Slightly soluble methanol and dimethyl sulfoxide. Insoluble in water.

Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Specifications

Chemical Identifiers

• CAS: 942-24-5
• Molecular Formula: C10H9NO2
• Molecular Weight (g/mol): 175.187
• MDL Number: MFCD00189407
• InChI Key: QXAUTQFAWKKNLM-UHFFFAOYSA-N
• Synonym: methyl indole-3-carboxylate, indole-3-carboxylic acid methyl ester, methyl 3-indolecarboxylate, 1h-indole-3-carboxylic acid methyl ester, 1h-indole-3-carboxylic acid, methyl ester, 3-carbomethoxyindole, 3-methoxycarbonylindole, methylindole-3-carboxylate, indole-3-carboxylic acid, methyl ester, methyl-3-indolcarboxylate
• PubChem CID: 589098
• ChEBI: CHEBI:65019
• IUPAC Name: methyl 1H-indole-3-carboxylate
• SMILES: COC(=O)C1=CNC2=CC=CC=C21

• Melting Point: 149°C to 152°C
• Quantity: 100 g
• Beilstein: 142023
• Solubility Information: Slightly soluble methanol and dimethyl sulfoxide. Insoluble in water.
• Formula Weight: 175.19
• Percent Purity: 99%
• Chemical Name or Material: Methyl indole-3-carboxylate

Safety and Handling

Hazard Category	H315-H319-H335
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only