Methylene Blue trihydrate

Description

Sensitive stain for RNA and ribonuclease | CAS: 7220-79-3 | C16H24ClN3O3S | 373.90 g/mol

Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.

Solubility
Soluble in water, alcohol and chloroform. Insoluble in ether.

Notes
Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 7220-79-3
• Molecular Formula: C16H24ClN3O3S
• Molecular Weight (g/mol): 373.90
• MDL Number: MFCD00150008
• InChI Key: XQAXGZLFSSPBMK-UHFFFAOYSA-M
• Synonym: C.I. 52015; Basic Blue 9
• PubChem CID: 104827
• IUPAC Name: [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate
• SMILES: O.O.O.[Cl-].CN(C)C1=CC2=[S+]C3=CC(=CC=C3N=C2C=C1)N(C)C

• Beilstein: 3599847
• Merck Index: 14,6060
• Solubility Information: Soluble in water,alcohol and chloroform; Insoluble in ether.
• Formula Weight: 373.90 (319.86 Anhydrous)
• Odor: Odorless
• Color: Green
• Quantity: 25 g
• Physical Form: Crystalline Powder
• Chemical Name or Material: Methylene Blue trihydrate

Safety and Handling

Hazard Category	H302
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P264b-P270-P301+P312-P330-P501c
EINECSNumber	200-515-2
RTECSNumber	SP5740000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only