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Methylene Blue trihydrate

Catalog No. AAJ6082330
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Catalog No. AAJ6082330 Supplier Thermo Scientific Chemicals Supplier No. J6082330
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Sensitive stain for RNA and ribonuclease | CAS: 7220-79-3 | C16H24ClN3O3S | 373.90 g/mol

Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.

Solubility
Soluble in water, alcohol and chloroform. Insoluble in ether.

Notes
Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 7220-79-3
Molecular Formula C16H24ClN3O3S
Molecular Weight (g/mol) 373.90
MDL Number MFCD00150008
InChI Key XQAXGZLFSSPBMK-UHFFFAOYSA-M
Synonym C.I. 52015; Basic Blue 9
PubChem CID 104827
IUPAC Name [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate
SMILES O.O.O.[Cl-].CN(C)C1=CC2=[S+]C3=CC(=CC=C3N=C2C=C1)N(C)C

Specifications

Beilstein 3599847
Merck Index 14,6060
Solubility Information Soluble in water,alcohol and chloroform; Insoluble in ether.
Formula Weight 373.90 (319.86 Anhydrous)
Odor Odorless
Color Green
Quantity 250 g
Physical Form Crystalline Powder
Chemical Name or Material Methylene Blue trihydrate
Hazard Category H302
Hazard Statement GHS H Statement
H302
Harmful if swallowed.
Precautionary Statement P264b-P270-P301+P312-P330-P501c
EINECSNumber 200-515-2
RTECSNumber SP5740000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only

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