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Medchemexpress LLC Methylhydroquinone | 95-71-6 | 99.9% | 124.14 | 1 KG
Supplier: Medchemexpress LLC HYW0128171KG
Methylhydroquinone is an orally active COX inhibitor with IC50s of 480.7 μM and 52.2 μM for ovine COX-1 and human recombinant COX-2, respectively. It has potential DNA damaging effects by inhibiting COX-1 to reduce prostaglandin synthesis and exert anti-inflammatory activity, and by inducing DNA single-strand breaks. Methylhydroquinone exerts its effects by competitively binding to the active sites of COX-1 (such as Tyr385, Met522) and non-covalent interactions. For research use only.
- Orally active COX inhibitor
- Inhibits COX-1 to reduce prostaglandin synthesis
- Exerts anti-inflammatory activity
- Induces DNA single-strand breaks
- Competitively binds to active sites of COX-1
- Non-covalent interactions
- Suitable for research use
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