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Medchemexpress LLC Methylhydroquinone | 95-71-6 | 99.9% | 124.14 | 100 G
SDP

Catalog No. 5000454972
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Methylhydroquinone is an orally active COX inhibitor with IC50s of 480.7 μM and 52.2 μM for ovine COX-1 and human recombinant COX-2, respectively. It has potential DNA damaging effects by inhibiting COX-1 to reduce prostaglandin synthesis and exert anti-inflammatory activity, and by inducing DNA single-strand breaks. Methylhydroquinone exerts its effects by competitively binding to the active sites of COX-1 (such as Tyr385, Met522) and non-covalent interactions. For research use only, not for sale to patients.

  • Orally active COX inhibitor
  • Inhibits COX-1 (IC50: 480.7 μM for ovine COX-1)
  • Inhibits COX-2 (IC50: 52.2 μM for human recombinant COX-2)
  • Potential DNA damaging effects: inhibits COX-1 to reduce prostaglandin synthesis and exert anti-inflammatory activity; induces DNA single-strand breaks
  • Competitively binds to active sites of COX-1 (e.g., Tyr385, Met522) via non-covalent interactions

Catalog No. 50-004-54972 Supplier Medchemexpress LLC Supplier No. HYW012817100G
May include imposed supplier surcharges.
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Methylhydroquinone is an orally active COX inhibitor with IC50s of 480.7 μM and 52.2 μM for ovine COX-1 and human recombinant COX-2, respectively. It has potential DNA damaging effects by inhibiting COX-1 to reduce prostaglandin synthesis and exert anti-inflammatory activity, and by inducing DNA single-strand breaks. Methylhydroquinone exerts its effects by competitively binding to the active sites of COX-1 (such as Tyr385, Met522) and non-covalent interactions. For research use only, not for sale to patients.

  • Orally active COX inhibitor
  • Inhibits COX-1 (IC50: 480.7 μM for ovine COX-1)
  • Inhibits COX-2 (IC50: 52.2 μM for human recombinant COX-2)
  • Potential DNA damaging effects: inhibits COX-1 to reduce prostaglandin synthesis and exert anti-inflammatory activity; induces DNA single-strand breaks
  • Competitively binds to active sites of COX-1 (e.g., Tyr385, Met522) via non-covalent interactions

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