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Methylphosphonic dichloride, 98%, Thermo Scientific™
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Quantity:
5g
Description
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
Applications
Methylphosphonic dichloride is used for the preparation of oligonucleotides. It is also used in Suzuki reaction. It serves as a precursor to several chemical weapon agents. Further, it reacts with hydrogen fluoride to get methylphosphonyl difluoride which is used in the production of sarin and soman nerve agents. In addition to this, it undergoes condensation reactions with aminobenzenes and alcohols.
Solubility
Soluble in water.
Notes
Moisture sensitive. Incompatible with strong bases, alcohols and strong oxidizing agents.
Methylphosphonic dichloride is used for the preparation of oligonucleotides. It is also used in Suzuki reaction. It serves as a precursor to several chemical weapon agents. Further, it reacts with hydrogen fluoride to get methylphosphonyl difluoride which is used in the production of sarin and soman nerve agents. In addition to this, it undergoes condensation reactions with aminobenzenes and alcohols.
Solubility
Soluble in water.
Notes
Moisture sensitive. Incompatible with strong bases, alcohols and strong oxidizing agents.

Specifications
Specifications
CAS | 676-97-1 |
Boiling Point | 59°C to 60°C (11mmHg) |
Flash Point | >110°C (230°F) |
Odor | Acrid |
Molecular Formula | CH3Cl2OP |
Quantity | 5g |
MDL Number | MFCD00002071 |
UN Number | UN2928 |
Beilstein | 1071305 |
Synonym | methylphosphonic dichloride, methylphosphonyl dichloride, methyl phosphonic dichloride, methanephosphonyl chloride, phosphonic dichloride, methyl, methanephosphonic dichloride, methylphosphonic acid dichloride, methylphosphonyl chloride, dichloromethylphosphine oxide, methylphosphonodichloridic acid |
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Safety and Handling
Hazard Category | Danger |
Hazard Statement | GHS H Statement H330-H314-H318 Fatal if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage. |
Precautionary Statement | GHS P Statement P260-P303+P361+P353-P304+P340-P305+P351+P338-P320-P405-P501a Do not breathe dust/fume/gas/mist/vapors/spray. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations. |
DOTInformation | Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, CORROSIVE, ORGANIC, N.O.S. |
RTECSNumber | TA1840000 |
TSCA | TSCA |
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