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Medchemexpress LLC Methylprednisolone succinate (sodium) | 2375-03-3 | ≥95% | 5 MG
Supplier: Medchemexpress LLC HYB10605MG
Methylprednisolone succinate sodium is a prodrug of Methylprednisolone and a glucocorticoid with immunosuppressant and anti-inflammatory activity. It binds cytosolic glucocorticoid receptors, translocates to nuclei, and modulates target gene transcription. This compound alters Bax, Bcl-2, occludin, and ZO-1 expression; attenuates TLR4/NF-κB signaling; and suppresses proinflammatory cytokine production and immune cell activation. It can be used for research of intracranial haemorrhage, rheumatoid arthritis, multiple sclerosis, preterminal cancer, inflammatory conditions, shock, immediate-type hypersensitivity, acute myocardial ischemia, hypoxic heart muscle damage, and traumatic spinal cord injury.
- Target: glucocorticoid receptor.
- Research areas: infection, neurological disease, inflammation/immunology, cancer.
- Immunosuppressant and anti-inflammatory activity.
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