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Cayman Chemical Methyltrnsferase asy S-Ade 1ea
Supplier: Cayman Chemical 7001461 EA
An anticancer polyamine inhibits the proliferation of PC3 TSU-pr1 DU145 and JCA-1 cells (IC50s 65 62 3 and 21 UM respectively) reduces ODC activity and increases diamine acetyltransferase 1 activity in PC3 DU145 and JCA-1 cells at 100 UM increases H2O2 levels and disrupts the mitochondrial membrane potential in U87 and LN-229 cells at 10 UM decreases tumor growth in a DU145 mouse xenograft model at 40 mg/kg three times per day
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