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Cayman Chemical MetIprnolol 10mg

Supplier: Cayman Chemical 3408910 MG
A β-AR antagonist; binds to primary rabbit iris and ciliary body homogenates (Ki = 34 nM); inhibits isoproterenol-induced relaxation in guinea pig atrium and fenoterol-induced relaxation in rat uterus (pA2s = 8.3 and 8.4, respectively); inhibits anoxia-induced cell death in primary rat retinal cells and sodium nitroprusside-induced lipid peroxidation in rat primary retinal homogenates (100 μM); decreases α-chymotrypsin-induced increases in IOP in rabbits when administered topically to the eye at a dose of 0.3%; inhibits the blinking response to ocular tactile stimulation in rabbits when administered topically to the eye at a dose of 0.6%
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