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Cayman Chemical MetIxenhydrochlorIde hydra 5mg
Supplier: Cayman Chemical 398255 MG
A muscarinic acetylcholine receptor antagonist (Ki = 15 nM for the rat receptor); inhibits bovine AChE by 43% at 10 µM and BChE (IC50 = 1.6 µM for the horse enzyme) in cell-free assays; reduces the proliferation of P388 and P388/ADR leukemia cells (EC50s = 10 and 12 µM, respectively); induces apoptosis in BT474 and MDA-MB-231 cancer cells at 15 µM and induces autophagy in the same cells at 10 µM; decreases tumor weight and volume and improves survival in an MDA-MB-231 breast cancer mouse xenograft model at 1 mg/kg three times per week
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