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Cayman Chemical MetoprololsuccInate 100mg
SDP

Supplier:  Cayman Chemical 15429100 MG

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A β1-AR antagonist (Ki = 47 nM in CHO cells expressing the human receptor); selective for β1- over β2- and β3-ARs (Kis = 2,730 and >10,000 nM, respectively, in CHO cells expressing the human receptors); reduces GTP-induced AC activity in CHO cells expressing β1- and β2-ARs at 4.7 µM; reduces the pulse rate in isolated rat atria in a concentration-dependent manner; reduces increased heart rate and MAP at 30 mg/kg in a rat model of systolic hypertension induced by a fructose-rich diet

Catalog No. 50-297-0625


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