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Enzo Life Sciences Mevastatin (10mg). CAS: 73573-88-3
Supplier: Enzo Life Sciences BMLG2330010
Mevastatin inhibits isoprenoid biosynthesis by inhibition of HMG-CoA reductase (Ki for acid form is 1 nM) and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. It causes cells to arrest early in the G1 phase. Mevastatin is a close structural analog of lovastatin and both agents have the same biochemical and pharmacological activities. Mevastatin is inactive in cell-free assays. In cells however, it is hydrolyzed to the active free acid form by intracellular esterases. Alternative name: Compactin. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO (20mg/ml) or 100% ethanol (25mg/ml). Long Term Storage: -20°C.
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