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Diagnostic Biosystems MGMT O(6)-Methylguanine-DNAMethyltransferase, MGMT
Supplier: Diagnostic Biosystems PDM423
O(6)-methylguanine-DNA-methyltransferase (MGMT) is a 22 kDa human DNA repair protein that removes O(6)-alkylguanine DNA adducts. MGMT acts as a suicide acceptor protein repairing the DNA by accepting alkyl groups and consequently inactivating itself. This antibody stains all mantle zone lymphocytes and 50% of germinal center lymphocytes. Basaloid epithelial cells of tonsilsquamous mucosa are also stained positive with this antibody.
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