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Medchemexpress LLC MI-389 | 2222635-92-7 | 99.3% | 654.69 | 50 MG
Supplier: Medchemexpress LLC HY13668850MG
MI-389 is a PROTAC translation termination factor GSPT1 degrader. It disrupts a target that is a shared dependency in various AML and ALL cell lines, and its action depends on the CRL4CRBN E3 ligase. This product is for research use only and is not sold to patients.
- Targets cereblon
- Exhibits antiproliferative activity in Kasumi 1 cells with an EC50 of 21.3 nM
- Appears as a yellow to orange solid
- Has a molecular formula of C35H35FN6O6
- Boasts a purity of 99.34%
- Soluble in DMSO at 66.67 mg/mL (101.83 mM)
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