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Medchemexpress LLC MI-463 | 1628317-18-9 | 99.7% | 484.54 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY19809100MG

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MI-463 is a highly potent and orally bioavailable small molecule inhibitor of the menin-mLL interaction.

  • Highly potent and orally bioavailable.
  • Inhibits menin-mLL interaction.
  • Achieves substantial growth inhibition of mLL-AF9 transformed mouse bone marrow cells.
  • Delays progression of mLL leukemia in murine models without toxicity.
  • Provides strong inhibition of tumor growth with once daily intraperitoneal administration.
  • Significantly reduces expression of mLL fusion protein target genes, HOXA9 and MEIS1.

Catalog No. 50-004-01875


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