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Medchemexpress LLC MI-773 | 1303607-07-9 | 96.3% | 562.50 | 100 MG

Supplier: Medchemexpress LLC HY17493100MG
MI-773 is a potent MDM2-p53 protein-protein interaction (PPI) inhibitor. It demonstrates high binding affinity against MDM2 and exhibits antitumor activity. An analog, MI-77301, shows even higher binding affinity and more pronounced antitumor activity in various p53 xenograft models.
- Potent MDM2-p53 protein-protein interaction (PPI) inhibitor.
- High binding affinity against MDM2 (Kd=8.2 nM).
- Exhibits antitumor activity.
- Analog shows enhanced binding affinity and antitumor activity.
- Effective in various p53 xenograft models including osteosarcoma, human prostate, melanoma, colorectal tumor, and human acute lymphoblastic leukemia.
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