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Medchemexpress LLC Midodrine (hydrochloride) | 43218-56-0 | 99.9% | 25 MG
Supplier: Medchemexpress LLC 25MGHY12749A
Midodrine hydrochloride is a selective and orally active adrenergic α1-receptor agonist. It strengthens vascular contraction and can be used for research on cardiovascular diseases such as orthostatic hypotension.
- Strengthens vascular contraction
- Increases p-AMPK and PPARδ expression in C2C12, HL1, and HepG2 cells
- Increases Ca2+ in C2C12, HL1, and HepG2 cells
- Increases maximal mitochondrial oxidative phosphorylation and ATP content in C2C12 cells
- Reduces cellular lipid content in 3T3-L1 cells
- Reduces platelet-activating factor (Paf)-induced death in mice
- Shows anti-hypotensive effects in orthostatic hypotension rat models
- Relieves hypertension in spontaneously hypertensive rat models
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