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Medchemexpress LLC Mifepristone | 84371-65-3 | 99.9% | 429.59 | 1 ML

Supplier: Medchemexpress LLC HY1368310MM/1ML
Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay. It was discovered as the first competitive progesterone antagonist, stimulating a search for more potent and selective antiprogestins.
- Progesterone receptor and glucocorticoid receptor antagonist
- Inhibits cell growth
- Potentiates doxorubicin-induced cytotoxicity in K562/R7 cells
- Reduces severity of EtOH withdrawal in vivo
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