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Medchemexpress LLC Migalastat (hydrochloride) | 75172-81-5 | ≥99.0% | 199.63 | 10MM/1ML
Supplier: Medchemexpress LLC HY14929A10MM/1ML
Migalastat hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. It functions by binding to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, it enables the mutant α-galactosidase A to exhibit biological activity.
- Binds to the active site of certain unstable mutant forms of α-galactosidase A
- Facilitates transport to the lysosome
- Enables mutant α-galactosidase A to exhibit biological activity
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