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Medchemexpress LLC Mindeudesivir hydrobromide | 2779498-79-0 | 98.2% | C24H31DBrN5O7 | 25 MG
Supplier: Medchemexpress LLC 25MGHY145119AS
Mindeudesivir hydrobromide (VV116) is a deuterated version of Remdesivir, a highly orally active nucleoside antiviral agent against SARS-CoV-2 and respiratory syncytial virus (RSV). It maintains the antiviral activity of Remdesivir against COVID-19 and is noted as the first domestically produced deuterium targeting COVID-19. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs, potentially offering several advantages.
- Used as a tracer or internal standard for quantitative analysis.
- Extends in vivo half-life and improves oral bioavailability.
- Improves metabolic characteristics and drug safety.
- Preserves therapeutic properties.
- Inhibits RSV replication in A549 cells.
- Shows strong antiviral activity against RSV in mice.
- Exhibits favorable pharmacokinetic properties and good safety profile.
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