Minoxidil

Description

Minoxidil, CAS # 38304-91-5, is a comopund with vasodilating effects that works by opening adenosine triphosphate (ATP)-sensitive potassium channels. | CAS: 38304-91-5 | C9H15N5O | 209.253 g/mol

Minoxidil is used as antihypertensive, antialopecia agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Minoxidil is a piperidine that acts as a vasodilator when converted into its active metabolite, minoxidil sulphate
• Minoxidil opens adenosine triphosphate (ATP)-sensitive potassium channels in the plasma membrane and relaxes smooth muscle in arteriole walls. Relaxation of smooth muscle within the arterioles leads to decreased resistance and lower blood pressure

Specifications

Chemical Identifiers

• CAS: 38304-91-5
• Molecular Formula: C9H15N5O
• Molecular Weight (g/mol): 209.253
• MDL Number: MFCD00063409
• InChI Key: ZIMGGGWCDYVHOY-UHFFFAOYSA-N
• Synonym: minoxidil, rogaine, loniten, regaine, minoximen, theroxidil, tricoxidil, alopexil, alostil, lonolox
• PubChem CID: 4201
• IUPAC Name: 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine
• SMILES: C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O

• Melting Point: 248°C to 265°C
• Color: White
• Quantity: 1 g
• Merck Index: 14,6203
• Solubility Information: Soluble in water (2.2mg/ml),100% ethanol (29mg/ml),propylene glycol,acetone,DMSO (6.5mg/ml),and methanol.
• Formula Weight: 209.25
• Physical Form: Crystalline Powder
• Chemical Name or Material: Minoxidil

Safety and Handling

Hazard Category	H302-H315-H319-H335
Hazard Statement	GHS H Statement H302-H315-H319-H335 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber	253-874-2
RTECSNumber	UV8200000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only